The alkaline reaction of nicotinamide adenine dinucleotide, a new transient intermediate.
نویسندگان
چکیده
In basic solutions NAD+ reversibly produces a 370 nm absorbing transient intermediate which irreversibly decomposes to a 340 run absorbing species. The concentration of the transient produced is proportional to the hydroxide concentration up to 5 M NaOH. NAD+ also undergoes an ionization reaction of the carboxamide NH, group, the K, of which is 7.3 x 10-13~. NMN undergoes spectral changes in alkaline solutions entirely analogous to those of NAD, and has a K, of 5.6 X lo-l3 M.
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عنوان ژورنال:
- The Journal of biological chemistry
دوره 245 17 شماره
صفحات -
تاریخ انتشار 1970